INEVITABILITY OF AGING
( Pp. 10-11)

Despite the rapid development of Biology, the causes and mechanisms of aging are still unclear [6]. There are several main theories of aging, explaining the very phenomenon of aging and its root causes. One of the dichotomy points of theories of aging is the question of the predetermination of aging: some theories postulate at a certain level the programmed nature of aging, while others postulate the randomness of the processes leading to aging. In recent studies, new theory of aging has been for-mulated. It is based on summary effect of non-utilized secondary products of biochemical reactions in cells. Thus it is possible to look at the aging process as a whole and to assume its inevitability.

Gusev F.O., (2017), INEVITABILITY OF AGING. Sociopolitical Sciences, 5 => 10-11.

Blagosklonny M.V. Aging: ROS or TOR //Cell cycle (Georgetown, Tex.). - 2008. - №21(7). - C.3344-3354.
Gladyshev V.N. The origin of aging: Imperfectness-driven non-random damage defines the aging process and control of lifespan //Trends in Genetics. - 2013. - №9 (29). - C.506-512.
Gladyshev V. N. Aging: progressive decline in fitness due to the rising deleteriome adjusted by ge-netic, environmental, and stochastic processes //Aging Cell. - 2016. - №4(15). - C.594-602.
Harman D. Aging: a theory based on free radical and radiation chemistry //Journal of gerontology. - 1956. - №3(11). - C.298-300.
Kirkwood T.B.L. Evolution of ageing. //Mechanisms of ageing and development. - 2002. - №7(123). - C.737-745.
Kirkwood T.B.L., Austad S.N. Why do we age //Nature. - 2000. - №6809(408). - C.233-238.
Kriete A. Robustness and aging-A systems-level perspective //BioSystems. 2013. - №1(112). - C.37-48.
Longo V. D., Mitteldorf J., Skulachev V.P. Programmed and altruistic ageing //Nature reviews. - Ge-netics. - 2005. - №11(6). - C.866-872.
Medawar P.B. An unsolved problem of biology /P.B.Medawar, College, 1952.
Orgel L. E. Ageing of clones of mammalian cells //Nature. - 1973. - №5408(243). - C.441-445.
Skulachev V.P. Aging is a specific biological function rather than the result of a disorder in com-plex living systems: biochemical evidence in support of Weismann s hypothesis //Biochemistry. - Bio-khimiia. - 1997. - №11(62). - C.1191-1195.
Weismann A. Ueber die Dauer des Lebens; ein Vortrag /A. Weismann, Jena: G. Fischer, 1882.
Williams G. C. Pleiotropy, Natural Selection, and the Evolution of Senescence //Evolution. - 1957. - №4(11). - C.398.

aging, theories of aging, predestination, accident.